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    Mattress Comparison
    Amerisleep AS4 mattress

    Amerisleep AS4

    VS
    Serta iSeries Hybrid mattress

    Serta iSeries Hybrid

    Amerisleep AS4 vs. Serta iSeries Hybrid

    Side-by-side comparison of the Amerisleep AS4 (Hybrid) and Serta iSeries Hybrid (Hybrid). Compare comfort, cooling, support, value and more — based on our lab testing.

    By Sleep Sage Editorial Team

    Side-by-side mattress testing · 144+ comparisons published

    Updated May 2026
    Category
    Amerisleep AS4
    Serta iSeries Hybrid
    Comfort
    9.5/10
    8.8/10
    Support
    8.5/10
    9/10
    Cooling
    8.8/10
    8.7/10
    Edge Support
    8.2/10
    9/10
    Motion Isolation
    9.2/10
    8.6/10
    Durability
    8.8/10
    8.9/10
    Value
    8.7/10
    8.5/10

    Quick Specs Comparison

    Spec
    Amerisleep AS4
    Serta iSeries Hybrid
    Price (Queen)
    $1,499
    $1,399
    Type
    Hybrid
    Hybrid
    Firmness
    4/10
    6/10
    Height
    12"
    12 inches
    Trial
    100 nights
    120 nights
    Warranty
    20 years
    10 years
    Shipping
    Free shipping
    Free shipping

    Key Advantages

    Why Choose Amerisleep AS4

    • Outstanding pressure relief for side sleepers
    • Deep contouring at shoulders and hips eliminates pressure points
    • Excellent motion isolation — ideal for couples

    Why Choose Serta iSeries Hybrid

    • Trusted 90+ year brand
    • Widely available in stores
    • Good balance of comfort and support

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